Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1975-12-4
pubmed:abstractText
In a patient with congenital absence of the uterus, daily measurements of progesterone (P), 17-hydroxyprogesterone (17-P), pregnenolone (delta5P), 17-hydroxypregnenolone (17-delta5P), dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), testosterone (T), dihydrotestosterone (DHT), androstenedione (A), estrone (E1), estradiol-17beta (E2), and cortisol (F) were performed over a period of 48 consecutive days. Serum P, 17-P, and E2 determinations revealed normal, cyclical ovarian activity consisting of two luteal phases and one follicular phase. Serum E1, delta5P, and DHEA-S levels were normal throughout the study, whereas DHEA and DHT levels were persistently elevated. Serum levels of 17-delta5P and A showed peak levels above normal. Serum T and F concentrations were normal during the initial part of the study, but some elevation was seen during the second luteal phase. In the patient studied, absence of the uterus did not seem to interfere with cyclic ovarian activity. The role of the uterus in the metabolism of androgens remains subject to further investigation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/17-alpha-Hydroxypregnenolone, http://linkedlifedata.com/resource/pubmed/chemical/Androstenedione, http://linkedlifedata.com/resource/pubmed/chemical/Dehydroepiandrosterone, http://linkedlifedata.com/resource/pubmed/chemical/Dihydrotestosterone, http://linkedlifedata.com/resource/pubmed/chemical/Estradiol, http://linkedlifedata.com/resource/pubmed/chemical/Estrone, http://linkedlifedata.com/resource/pubmed/chemical/Hydrocortisone, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyprogesterones, http://linkedlifedata.com/resource/pubmed/chemical/Luteinizing Hormone, http://linkedlifedata.com/resource/pubmed/chemical/Pregnanolone, http://linkedlifedata.com/resource/pubmed/chemical/Progesterone, http://linkedlifedata.com/resource/pubmed/chemical/Steroids, http://linkedlifedata.com/resource/pubmed/chemical/Testosterone
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0029-7844
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
320-22
pubmed:dateRevised
2009-10-26
pubmed:meshHeading
pubmed-meshheading:125866-17-alpha-Hydroxypregnenolone, pubmed-meshheading:125866-Adolescent, pubmed-meshheading:125866-Amenorrhea, pubmed-meshheading:125866-Androstenedione, pubmed-meshheading:125866-Dehydroepiandrosterone, pubmed-meshheading:125866-Dihydrotestosterone, pubmed-meshheading:125866-Estradiol, pubmed-meshheading:125866-Estrone, pubmed-meshheading:125866-Female, pubmed-meshheading:125866-Follicular Phase, pubmed-meshheading:125866-Humans, pubmed-meshheading:125866-Hydrocortisone, pubmed-meshheading:125866-Hydroxyprogesterones, pubmed-meshheading:125866-Karyotyping, pubmed-meshheading:125866-Luteal Phase, pubmed-meshheading:125866-Luteinizing Hormone, pubmed-meshheading:125866-Pregnanolone, pubmed-meshheading:125866-Progesterone, pubmed-meshheading:125866-Steroids, pubmed-meshheading:125866-Testosterone, pubmed-meshheading:125866-Uterus
pubmed:year
1975
pubmed:articleTitle
Peripheral steroid levels in a patient with congenital absence of the uterus.
pubmed:publicationType
Journal Article