| pubmed-article:12581658 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12581658 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:12581658 | lifeskim:mentions | umls-concept:C1704241 | lld:lifeskim |
| pubmed-article:12581658 | lifeskim:mentions | umls-concept:C0220905 | lld:lifeskim |
| pubmed-article:12581658 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:12581658 | pubmed:dateCreated | 2003-2-12 | lld:pubmed |
| pubmed-article:12581658 | pubmed:abstractText | It is characteristic of eukaryotic transcription that a unique combination of multiple transcriptional regulatory proteins bound to promoter DNA specifically activate or repress downstream target genes; this is referred to as combinatorial gene regulation. Recently determined structures have revealed different modes of protein-protein interaction on the promoter DNA from near (e.g. the Runx1-CBFbeta-DNA, NFAT-Fos-Jun-DNA, GABPalpha-GABPbeta-DNA, Ets-1-Pax-5-DNA and PU.1-IRF-4-DNA complexes) and afar with DNA looping (e.g. the c-Myb-C/EBPbeta-DNA complex), and their regulatory mechanisms. | lld:pubmed |
| pubmed-article:12581658 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12581658 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12581658 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12581658 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12581658 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12581658 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:12581658 | pubmed:issn | 0959-440X | lld:pubmed |
| pubmed-article:12581658 | pubmed:author | pubmed-author:TahirovTahir... | lld:pubmed |
| pubmed-article:12581658 | pubmed:author | pubmed-author:SatoKoK | lld:pubmed |
| pubmed-article:12581658 | pubmed:author | pubmed-author:OgataKazuhiro... | lld:pubmed |
| pubmed-article:12581658 | pubmed:author | pubmed-author:TahirovTahirT | lld:pubmed |
| pubmed-article:12581658 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12581658 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:12581658 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12581658 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12581658 | pubmed:pagination | 40-8 | lld:pubmed |
| pubmed-article:12581658 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:12581658 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12581658 | pubmed:articleTitle | Eukaryotic transcriptional regulatory complexes: cooperativity from near and afar. | lld:pubmed |
| pubmed-article:12581658 | pubmed:affiliation | Department of Biochemistry, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. ogata@med.yokohama-cu.ac.jp | lld:pubmed |
| pubmed-article:12581658 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12581658 | pubmed:publicationType | Review | lld:pubmed |
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