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rdf:type |
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lifeskim:mentions |
umls-concept:C0003753,
umls-concept:C0016030,
umls-concept:C0017262,
umls-concept:C0026724,
umls-concept:C0029172,
umls-concept:C0035820,
umls-concept:C0041904,
umls-concept:C0086418,
umls-concept:C0162493,
umls-concept:C0185117,
umls-concept:C0387583,
umls-concept:C0442010,
umls-concept:C0699748,
umls-concept:C2911684
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pubmed:issue |
3
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pubmed:dateCreated |
2003-2-12
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pubmed:abstractText |
Aberrant and persistent tissue inflammation are believed to play an important role on the occurrence of tissue fibrosis. Cyclooxygenase (COX)-2 is an inducible enzyme responsible for prostaglandin synthesis in certain inflammatory diseases. The purpose of this study was to compare COX-2 expression in normal human buccal mucosa and oral submucous fibrosis (OSF) specimens and further explore the potential mechanism that may lead to induce COX-2 expression.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-oxothiazolidine-4-carboxylic acid,
http://linkedlifedata.com/resource/pubmed/chemical/Arecoline,
http://linkedlifedata.com/resource/pubmed/chemical/Aspirin,
http://linkedlifedata.com/resource/pubmed/chemical/Buthionine Sulfoximine,
http://linkedlifedata.com/resource/pubmed/chemical/Cholinergic Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2 Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/N-(2-cyclohexyloxy-4-nitrophenyl)met...,
http://linkedlifedata.com/resource/pubmed/chemical/Nitrobenzenes,
http://linkedlifedata.com/resource/pubmed/chemical/PTGS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Peroxidases,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin-Endoperoxide Synthases,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrrolidonecarboxylic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazolidines
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0904-2512
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
146-53
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12581384-Arecoline,
pubmed-meshheading:12581384-Aspirin,
pubmed-meshheading:12581384-Buthionine Sulfoximine,
pubmed-meshheading:12581384-Cell Culture Techniques,
pubmed-meshheading:12581384-Cholinergic Agonists,
pubmed-meshheading:12581384-Cyclooxygenase 2,
pubmed-meshheading:12581384-Cyclooxygenase 2 Inhibitors,
pubmed-meshheading:12581384-Cyclooxygenase Inhibitors,
pubmed-meshheading:12581384-Endothelium, Vascular,
pubmed-meshheading:12581384-Enzyme Inhibitors,
pubmed-meshheading:12581384-Epithelial Cells,
pubmed-meshheading:12581384-Fibroblasts,
pubmed-meshheading:12581384-Glutathione,
pubmed-meshheading:12581384-Humans,
pubmed-meshheading:12581384-Immunohistochemistry,
pubmed-meshheading:12581384-Isoenzymes,
pubmed-meshheading:12581384-Matched-Pair Analysis,
pubmed-meshheading:12581384-Membrane Proteins,
pubmed-meshheading:12581384-Mouth Mucosa,
pubmed-meshheading:12581384-Nitrobenzenes,
pubmed-meshheading:12581384-Oral Submucous Fibrosis,
pubmed-meshheading:12581384-Peroxidases,
pubmed-meshheading:12581384-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:12581384-Pyrrolidonecarboxylic Acid,
pubmed-meshheading:12581384-Sulfonamides,
pubmed-meshheading:12581384-Thiazoles,
pubmed-meshheading:12581384-Thiazolidines,
pubmed-meshheading:12581384-Transcription, Genetic,
pubmed-meshheading:12581384-Up-Regulation
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pubmed:year |
2003
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pubmed:articleTitle |
The up-regulation of cyclooxygenase-2 expression in human buccal mucosal fibroblasts by arecoline: a possible role in the pathogenesis of oral submucous fibrosis.
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pubmed:affiliation |
Department of Pathology, Chung Shan Medical University Hospital, Taichung, Taiwan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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