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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0008546,
umls-concept:C0029974,
umls-concept:C0043342,
umls-concept:C0439201,
umls-concept:C0920283,
umls-concept:C1140108,
umls-concept:C1167124,
umls-concept:C1332724,
umls-concept:C1417504,
umls-concept:C1555707,
umls-concept:C1705851,
umls-concept:C1879547,
umls-concept:C2752151,
umls-concept:C2828366
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pubmed:issue |
2
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pubmed:dateCreated |
2003-2-12
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pubmed:abstractText |
MCM and Cdc45 are required for the initiation and elongation stages of eukaryotic DNA replication. Recent studies show that a purified Mcm4/6/7 complex has DNA helicase activity. However, the biochemical function of the MCM complex and Cdc45 bound to chromatin has not been elucidated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1356-9597
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
145-61
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12581157-Animals,
pubmed-meshheading:12581157-Carrier Proteins,
pubmed-meshheading:12581157-Cell Extracts,
pubmed-meshheading:12581157-Chromatin,
pubmed-meshheading:12581157-Cyclin-Dependent Kinases,
pubmed-meshheading:12581157-DNA Helicases,
pubmed-meshheading:12581157-DNA Replication,
pubmed-meshheading:12581157-DNA-Binding Proteins,
pubmed-meshheading:12581157-Enzyme Activation,
pubmed-meshheading:12581157-Models, Biological,
pubmed-meshheading:12581157-Nuclear Proteins,
pubmed-meshheading:12581157-Oocytes,
pubmed-meshheading:12581157-Phosphorylation,
pubmed-meshheading:12581157-S Phase,
pubmed-meshheading:12581157-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:12581157-Xenopus
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pubmed:year |
2003
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pubmed:articleTitle |
CDK- and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45.
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pubmed:affiliation |
Department of Biology, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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