pubmed-article:12575952 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C0521390 | lld:lifeskim |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C1179435 | lld:lifeskim |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C1414142 | lld:lifeskim |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C0439799 | lld:lifeskim |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C1705248 | lld:lifeskim |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C1511545 | lld:lifeskim |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C1548799 | lld:lifeskim |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C1524073 | lld:lifeskim |
pubmed-article:12575952 | lifeskim:mentions | umls-concept:C0449432 | lld:lifeskim |
pubmed-article:12575952 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:12575952 | pubmed:dateCreated | 2003-2-10 | lld:pubmed |
pubmed-article:12575952 | pubmed:abstractText | Subthreshold-activating somatodendritic A-type potassium channels have fundamental roles in neuronal signaling and plasticity which depend on their unique cellular localization, voltage dependence, and kinetic properties. Some of the components of A-type K(+) channels have been identified; however, these do not reproduce the properties of the native channels, indicating that key molecular factors have yet to be unveiled. We purified A-type K(+) channel complexes from rat brain membranes and found that DPPX, a protein of unknown function that is structurally related to the dipeptidyl aminopeptidase and cell adhesion protein CD26, is a novel component of A-type K(+) channels. DPPX associates with the channels' pore-forming subunits, facilitates their trafficking and membrane targeting, reconstitutes the properties of the native channels in heterologous expression systems, and is coexpressed with the pore-forming subunits in the somatodendritic compartment of CNS neurons. | lld:pubmed |
pubmed-article:12575952 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12575952 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12575952 | pubmed:language | eng | lld:pubmed |
pubmed-article:12575952 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12575952 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:12575952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12575952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12575952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12575952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:12575952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12575952 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12575952 | pubmed:month | Feb | lld:pubmed |
pubmed-article:12575952 | pubmed:issn | 0896-6273 | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:MisumiYoshioY | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:MaYuliangY | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:RudyBernardoB | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:NeubertThomas... | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:MoWenjunW | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:Vega-Saenz... | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:NadalMarcela... | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:OzaitaAndrésA | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:AmarilloYimyY | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:GoldbergEthan... | lld:pubmed |
pubmed-article:12575952 | pubmed:author | pubmed-author:IkeharaYukioY | lld:pubmed |
pubmed-article:12575952 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12575952 | pubmed:day | 6 | lld:pubmed |
pubmed-article:12575952 | pubmed:volume | 37 | lld:pubmed |
pubmed-article:12575952 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12575952 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12575952 | pubmed:pagination | 449-61 | lld:pubmed |
pubmed-article:12575952 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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pubmed-article:12575952 | pubmed:year | 2003 | lld:pubmed |
pubmed-article:12575952 | pubmed:articleTitle | The CD26-related dipeptidyl aminopeptidase-like protein DPPX is a critical component of neuronal A-type K+ channels. | lld:pubmed |
pubmed-article:12575952 | pubmed:affiliation | Department of Physiology and Neuroscience and Department of Biochemistry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA. | lld:pubmed |
pubmed-article:12575952 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:12575952 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:12575952 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
pubmed-article:12575952 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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