Source:http://linkedlifedata.com/resource/pubmed/id/12572723
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2003-2-7
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pubmed:abstractText |
Ozonized sunflower oil, Oleozon, has a remarkable gerrmicidal action. In the present study, the efficacy of Oleozon in the treatment of tinea pedis was demonstrated in a controlled randomized phase III assay, comparing topical Oleozon with ketoconazole cream 2% (Nizoral) in 200 patients (100 in each group). The treatment administered was twice per day for a period of 6 weeks. The efficacy was evaluated clinically (disappearance of all lesions, with or without negative mycological results) and mycologically (negative culture results). A complete clinical and mycological cure was obtained in 75 and 81% for Oleozon and ketoconazole, respectively, with no significant differences between both groups. No side-effects or bacterial super-infections were observed. Patients were evaluated 6 months after the end of the treatment and no recurrence was observed in the Oleozon group. Oleozon can be an effective alternative low-cost antimycotic drug.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antifungal Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Ketoconazole,
http://linkedlifedata.com/resource/pubmed/chemical/Ozone,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Oils,
http://linkedlifedata.com/resource/pubmed/chemical/sunflower seed oil
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0933-7407
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
329-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12572723-Adolescent,
pubmed-meshheading:12572723-Adult,
pubmed-meshheading:12572723-Antifungal Agents,
pubmed-meshheading:12572723-Candida albicans,
pubmed-meshheading:12572723-Epidermophyton,
pubmed-meshheading:12572723-Female,
pubmed-meshheading:12572723-Humans,
pubmed-meshheading:12572723-Ketoconazole,
pubmed-meshheading:12572723-Male,
pubmed-meshheading:12572723-Ozone,
pubmed-meshheading:12572723-Plant Oils,
pubmed-meshheading:12572723-Tinea Pedis,
pubmed-meshheading:12572723-Treatment Outcome,
pubmed-meshheading:12572723-Trichophyton
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pubmed:year |
2002
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pubmed:articleTitle |
Efficacy of ozonized sunflower oil in the treatment of tinea pedis.
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pubmed:affiliation |
Centro de Investigaciones del Ozono, Apartado Postal 6880, Playa, Cuba. ozono@infomed.sld.cu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase III
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