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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2003-2-6
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pubmed:abstractText |
Biochemical, genetic, and clinical evidence indicates that smooth-muscle proliferation around small pulmonary vessels is an essential part of the pathogenesis of pulmonary hypertension. Mutations in the bone morphogenetic protein receptor type 2 (BMPR2) have been linked to familial cases of pulmonary hypertension, but the molecular basis of the common nonfamilial forms is unknown.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ANGPT1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Activin Receptors, Type I,
http://linkedlifedata.com/resource/pubmed/chemical/Angiogenesis Inducing Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Angiopoietin-1,
http://linkedlifedata.com/resource/pubmed/chemical/BMPR1A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/BMPR2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Protein...,
http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Protein...,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, TIE-2,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Growth Factor
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1533-4406
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2003 Massachusetts Medical Society
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pubmed:issnType |
Electronic
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pubmed:day |
6
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pubmed:volume |
348
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
500-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12571257-Activin Receptors, Type I,
pubmed-meshheading:12571257-Angiogenesis Inducing Agents,
pubmed-meshheading:12571257-Angiopoietin-1,
pubmed-meshheading:12571257-Bone Morphogenetic Protein Receptors, Type I,
pubmed-meshheading:12571257-Bone Morphogenetic Protein Receptors, Type II,
pubmed-meshheading:12571257-Gene Expression Regulation,
pubmed-meshheading:12571257-Humans,
pubmed-meshheading:12571257-Hypertension, Pulmonary,
pubmed-meshheading:12571257-Lung,
pubmed-meshheading:12571257-Membrane Glycoproteins,
pubmed-meshheading:12571257-Phosphorylation,
pubmed-meshheading:12571257-Protein-Serine-Threonine Kinases,
pubmed-meshheading:12571257-RNA, Messenger,
pubmed-meshheading:12571257-Receptor, TIE-2,
pubmed-meshheading:12571257-Receptor Protein-Tyrosine Kinases,
pubmed-meshheading:12571257-Receptors, Growth Factor,
pubmed-meshheading:12571257-Severity of Illness Index,
pubmed-meshheading:12571257-Signal Transduction,
pubmed-meshheading:12571257-Transcription, Genetic
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pubmed:year |
2003
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pubmed:articleTitle |
Signaling molecules in nonfamilial pulmonary hypertension.
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pubmed:affiliation |
Division of Cardiothoracic Surgery, University of California, San Diego, San Diego CA 92103-8892, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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