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pubmed-article:12569602pubmed:abstractTextPulmonary aspergillosis and other invasive fungal infections (IFIs) commonly complicate the management of patients with acute leukemia. Standard amphotericin-based therapies may be ineffective for many patients and the available salvage agents (itraconazole and caspofungin) are reported to possess only moderate activity against resistant infections. Laboratory evidence suggests a synergistic interaction between amphotericin and caspofungin. The authors treated a group of patients with amphotericin-refractory IFIs with the combination of caspofungin and amphotericin (or liposomal amphotericin).lld:pubmed
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pubmed-article:12569602pubmed:copyrightInfoCopyright 2003 American Cancer Societylld:pubmed
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pubmed-article:12569602pubmed:articleTitleRefractory Aspergillus pneumonia in patients with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericin.lld:pubmed
pubmed-article:12569602pubmed:affiliationLeukemia Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.lld:pubmed
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