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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2003-2-5
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pubmed:abstractText |
Pulmonary aspergillosis and other invasive fungal infections (IFIs) commonly complicate the management of patients with acute leukemia. Standard amphotericin-based therapies may be ineffective for many patients and the available salvage agents (itraconazole and caspofungin) are reported to possess only moderate activity against resistant infections. Laboratory evidence suggests a synergistic interaction between amphotericin and caspofungin. The authors treated a group of patients with amphotericin-refractory IFIs with the combination of caspofungin and amphotericin (or liposomal amphotericin).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2003 American Cancer Society
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1025-32
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12569602-Acute Disease,
pubmed-meshheading:12569602-Adult,
pubmed-meshheading:12569602-Aged,
pubmed-meshheading:12569602-Amphotericin B,
pubmed-meshheading:12569602-Anti-Bacterial Agents,
pubmed-meshheading:12569602-Aspergillosis,
pubmed-meshheading:12569602-Drug Therapy, Combination,
pubmed-meshheading:12569602-Echinocandins,
pubmed-meshheading:12569602-Female,
pubmed-meshheading:12569602-Humans,
pubmed-meshheading:12569602-Leukemia,
pubmed-meshheading:12569602-Lung Diseases, Fungal,
pubmed-meshheading:12569602-Male,
pubmed-meshheading:12569602-Middle Aged,
pubmed-meshheading:12569602-Peptides,
pubmed-meshheading:12569602-Peptides, Cyclic,
pubmed-meshheading:12569602-Pneumonia,
pubmed-meshheading:12569602-Retrospective Studies
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pubmed:year |
2003
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pubmed:articleTitle |
Refractory Aspergillus pneumonia in patients with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericin.
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pubmed:affiliation |
Leukemia Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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