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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2003-2-5
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pubmed:abstractText |
Although as many as 10% of pancreatic cancer cases may have an inherited component, familial pancreatic cancer has not been linked to defects in any specific gene. Some studies have shown that families with germline mutations in the breast cancer susceptibility gene BRCA2 have an increased risk of breast and ovarian cancers, as well as a modestly increased risk of pancreatic cancer. To study these relationships in more detail, we examined whether BRCA2 germline mutations are associated with familial pancreatic cancer.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0027-8874
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pubmed:author |
pubmed-author:BartschDetlef KDK,
pubmed-author:CampraDonataD,
pubmed-author:EllisIanI,
pubmed-author:GerdesBertholdB,
pubmed-author:GrützmannRobertR,
pubmed-author:GreenhalfBillB,
pubmed-author:HahnStephan ASA,
pubmed-author:KorteBirgitB,
pubmed-author:KressRalfR,
pubmed-author:NeoptolemosJohn PJP,
pubmed-author:RaeburnJohn AJA,
pubmed-author:RehderHelgaH,
pubmed-author:RiederHaraldH,
pubmed-author:RothmundMatthiasM,
pubmed-author:SchmiegelWolffW,
pubmed-author:Sina-FreyMercedesM,
pubmed-author:ZieglerAndreasA
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pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
214-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12569143-Adult,
pubmed-meshheading:12569143-Aged,
pubmed-meshheading:12569143-DNA, Neoplasm,
pubmed-meshheading:12569143-Europe,
pubmed-meshheading:12569143-Female,
pubmed-meshheading:12569143-Frameshift Mutation,
pubmed-meshheading:12569143-Genes, BRCA2,
pubmed-meshheading:12569143-Genetic Predisposition to Disease,
pubmed-meshheading:12569143-Germ-Line Mutation,
pubmed-meshheading:12569143-Germany,
pubmed-meshheading:12569143-Humans,
pubmed-meshheading:12569143-Lymphocytes,
pubmed-meshheading:12569143-Male,
pubmed-meshheading:12569143-Middle Aged,
pubmed-meshheading:12569143-Pancreatic Neoplasms,
pubmed-meshheading:12569143-Pedigree,
pubmed-meshheading:12569143-Phenotype,
pubmed-meshheading:12569143-Registries,
pubmed-meshheading:12569143-Sequence Analysis, DNA
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pubmed:year |
2003
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pubmed:articleTitle |
BRCA2 germline mutations in familial pancreatic carcinoma.
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pubmed:affiliation |
Department of Internal Medicine, Knappschaftskrankenhaus University of Bochum, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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