Source:http://linkedlifedata.com/resource/pubmed/id/12568819
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2003-2-5
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pubmed:abstractText |
Family history assessment can be used to combine population-wide health promotion and risk-reduction efforts with a high-risk, targeted approach to help reduce the burden of cardiovascular disease (CVD). Family history is an independent predictor of CVD, and the upper portion of the family history distribution explains a larger fraction of CVD in the population than can be explained by extreme values of other risk factors (e.g., blood pressure and cholesterol). A positive family history of disease captures the underlying complexities of gene-gene and gene-environment interactions by identifying families with combinations of risk factors, both measured and unmeasured, that lead to disease expression. Family history is a useful tool for identifying most prevalent cases of CVD and for population-wide disease-prevention efforts. A positive family history also identifies the relatively small subset of families in the population at highest risk for CVD who may benefit most from targeted screening and intensive intervention.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0749-3797
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
136-42
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12568819-Cardiovascular Diseases,
pubmed-meshheading:12568819-Cost-Benefit Analysis,
pubmed-meshheading:12568819-Family,
pubmed-meshheading:12568819-Genetic Predisposition to Disease,
pubmed-meshheading:12568819-Humans,
pubmed-meshheading:12568819-Mass Screening,
pubmed-meshheading:12568819-Medical History Taking,
pubmed-meshheading:12568819-Predictive Value of Tests,
pubmed-meshheading:12568819-Primary Prevention,
pubmed-meshheading:12568819-Risk Assessment,
pubmed-meshheading:12568819-Risk Factors
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pubmed:year |
2003
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pubmed:articleTitle |
Family history assessment: strategies for prevention of cardiovascular disease.
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pubmed:affiliation |
Cardiovascular Genetics Research Program, Department of Internal Medicine, University of Utah School of Medicine, 410 Chipeta Way, Room 167, Salt Lake City, UT 84108, USA. steve@ucvg.med.utah.edu
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pubmed:publicationType |
Journal Article
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