Linked Life Data

12559813

Source:http://linkedlifedata.com/resource/pubmed/id/12559813

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2003-1-31
pubmed:abstractText
In this paper the semi-interpenetrating network (semi-IPN) technique was used for the first time to prepare bone implant composites containing hydroxyapatite (HAP) nanocrystals. The prepared nanocomposites are expected to combine several property advantages including good mechanical strength, modified degradation rate and excellent osteoconductivity. The semi-IPN matrix based on the linear poly (epsilon-caprolactone) (L-PCL) and the network poly (epsilon-caprolactone) (net-PCL) structures are revealed to be phase separation structures. The morphology of net-PCL is featured by intracrosslinked microdomains (1-10 microm) that further interconnect with each other to form the network over the whole sample. The net-PCL component is totally amorphous at room temperature for the nanocomposites containing HAP up to 12.3 wt%. Further, the crystallinity of L-PCL is greatly decreased due to the presence of net-PCL as compared with that for pure L-PCL. The incorporation of L-PCL into the net-PCL network could significantly improve the mechanical properties of pure net-PCL. A great improvement in mechanical properties is observed for the nanocomposites if the HAP content is increased to 15.8 wt%. This transition is in agreement with that the net-PCL component changes from amorphous state to crystalline state at this composition.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0142-9612
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1531-9
pubmed:dateRevised
2008-8-14
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Investigation of nanocomposites based on semi-interpenetrating network of [L-poly (epsilon-caprolactone)]/[net-poly (epsilon-caprolactone)] and hydroxyapatite nanocrystals.
pubmed:affiliation
Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Academia Sinica, P.O. Box 415, Chengdu 610041, People's Republic of China. jianyuan.hao@nottingham.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't