Source:http://linkedlifedata.com/resource/pubmed/id/12558783
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-1-31
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pubmed:abstractText |
An orthopaedic assessment of the joint status of seven severe haemophiliacs (mean age 12.5 y - range 8.9-15.5) on prophylactic treatment (PT) by magnetic resonance imaging (MRI) and physical examination was carried out. Median duration of PT of these patients was 84 months (range 32-107). A locally designed MRI joint score considering seven parameters (1 - joint effusion, 2 - synovial membrane thickening, 3 - haemosiderin deposits, 4 - joint cartilage injury, 5 - subchondral bone erosion, 6 - subchondral bone cysts, 7 - osteonecrosis) was used (maximum score = 13 points). MRI scans were performed in 17 joints (nine ankles, seven knees and one elbow): mean MRI scores for the affected joints was 5.1. A poor consistency between physical examination and MRI findings or the real extent of joint damage was found (Cohen kappa index 0.320). MRI is a precise non-invasive tool for the assessment of early joint cartilage and synovium pathological changes still undetectable by physical examination or conventional X-rays in the haemophilic setting.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1351-8216
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
76-85
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pubmed:dateRevised |
2009-10-21
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pubmed:meshHeading |
pubmed-meshheading:12558783-Adolescent,
pubmed-meshheading:12558783-Child,
pubmed-meshheading:12558783-Factor IX,
pubmed-meshheading:12558783-Factor VIII,
pubmed-meshheading:12558783-Follow-Up Studies,
pubmed-meshheading:12558783-Hemarthrosis,
pubmed-meshheading:12558783-Hemophilia A,
pubmed-meshheading:12558783-Hemophilia B,
pubmed-meshheading:12558783-Humans,
pubmed-meshheading:12558783-Magnetic Resonance Imaging,
pubmed-meshheading:12558783-Male,
pubmed-meshheading:12558783-Physical Examination,
pubmed-meshheading:12558783-Prospective Studies
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pubmed:year |
2003
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pubmed:articleTitle |
Value of magnetic resonance imaging for the diagnosis and follow-up of haemophilic arthropathy.
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pubmed:affiliation |
Department of Haematology, Hospital Miguel Servet, Zaragoza, Spain.
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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