Source:http://linkedlifedata.com/resource/pubmed/id/12553360
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2003-1-29
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pubmed:abstractText |
Ultraviolet radiation (UV) damaged-DNA binding (DDB) activity comprises two major components: damaged-DNA binding protein 1 (DDB1) and 2 (DDB2). Although the function of DDB is unclear, mutation on DDB2 is associated with cellular sensitivity to a variety of genotoxic agents including UV. It has been suggested that DDB2 may play a role in UV-induced DNA repair. However, evidence that DDB2 involves in DNA repair and UV sensitivity is lacking.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
2072-0939
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
723-33
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pubmed:dateRevised |
2008-12-16
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pubmed:meshHeading |
pubmed-meshheading:12553360-Animals,
pubmed-meshheading:12553360-Apoptosis,
pubmed-meshheading:12553360-Cell Line,
pubmed-meshheading:12553360-Cricetinae,
pubmed-meshheading:12553360-DNA Damage,
pubmed-meshheading:12553360-DNA Repair,
pubmed-meshheading:12553360-DNA-Binding Proteins,
pubmed-meshheading:12553360-Humans,
pubmed-meshheading:12553360-Plasmids,
pubmed-meshheading:12553360-Radiation Tolerance,
pubmed-meshheading:12553360-Ultraviolet Rays
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pubmed:year |
2002
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pubmed:articleTitle |
Overexpression of damaged-DNA-binding protein 2 (DDB2) potentiates UV resistance in hamster V79 cells.
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pubmed:affiliation |
Tumor Biology Laboratory, Department of Biochemistry, Chang Gung University, Taoyuan, Taiwan, ROC.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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