rdf:type |
|
lifeskim:mentions |
umls-concept:C0020971,
umls-concept:C0021756,
umls-concept:C0200635,
umls-concept:C0442805,
umls-concept:C0871261,
umls-concept:C1274040,
umls-concept:C1332714,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2349975,
umls-concept:C2911692
|
pubmed:issue |
2
|
pubmed:dateCreated |
2003-1-28
|
pubmed:abstractText |
To ascertain whether CD4(+) lymphocyte increases induced by interleukin (IL)-2 enhanced in vivo immune responses, 38 human immunodeficiency virus (HIV)-infected patients who had received highly active antiretroviral therapy (HAART) or HAART and IL-2 for at least 60 weeks were immunized with tetanus toxoid, inactivated glycoprotein 120-depleted HIV-1, and hepatitis A and B vaccines. Despite dramatic increases in CD4(+) lymphocyte counts, IL-2 did not enhance immunization responses.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0022-1899
|
pubmed:author |
pubmed-author:ChanEllen SES,
pubmed-author:EstepScharlaS,
pubmed-author:FaheyJohnJ,
pubmed-author:FoxLawrenceL,
pubmed-author:KalamsSpyros ASA,
pubmed-author:LandayAlanA,
pubmed-author:LedermanMichael MMM,
pubmed-author:MitsuyasuRonaldR,
pubmed-author:MossRonaldR,
pubmed-author:NamkungAnnA,
pubmed-author:PollardRichard BRB,
pubmed-author:SahnerDavidD,
pubmed-author:SevinAnne DAD,
pubmed-author:SpritzlerJohnJ,
pubmed-author:ValdezHernanH
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
187
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
320-5
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:12552459-AIDS Vaccines,
pubmed-meshheading:12552459-Adjuvants, Immunologic,
pubmed-meshheading:12552459-Adult,
pubmed-meshheading:12552459-Anti-HIV Agents,
pubmed-meshheading:12552459-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:12552459-CD4 Lymphocyte Count,
pubmed-meshheading:12552459-CD4-Positive T-Lymphocytes,
pubmed-meshheading:12552459-Drug Therapy, Combination,
pubmed-meshheading:12552459-HIV Infections,
pubmed-meshheading:12552459-Hepatitis A Vaccines,
pubmed-meshheading:12552459-Hepatitis B Vaccines,
pubmed-meshheading:12552459-Humans,
pubmed-meshheading:12552459-Interleukin-2,
pubmed-meshheading:12552459-Lymphocyte Activation,
pubmed-meshheading:12552459-Male,
pubmed-meshheading:12552459-Tetanus Toxoid
|
pubmed:year |
2003
|
pubmed:articleTitle |
Interleukin-2 Increases CD4+ lymphocyte numbers but does not enhance responses to immunization: results of A5046s.
|
pubmed:affiliation |
Case Western Reserve University and University Hospitals of Cleveland, Ohio 44106, USA. valdez.hernan@clevelandactu.org
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.
|