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pubmed-article:12552458pubmed:abstractTextProteins may serve as ideal CD8(+) T cell immunogens for human immunodeficiency virus type 1 (HIV-1) if they can be delivered to and processed through the human leukocyte antigen class I pathway. This study shows that human blood monocyte-derived dendritic cells loaded with liposome-complexed HIV-1 proteins and matured with CD40 ligand can prime CD8(+) T cells to HIV-1 in vitro. Whole HIV-1 protein in liposome may be an effective immunogen for HIV-1 vaccine protocols.lld:pubmed
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pubmed-article:12552458pubmed:articleTitlePriming of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cell responses by dendritic cells loaded with HIV-1 proteins.lld:pubmed
pubmed-article:12552458pubmed:affiliationGraduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA.lld:pubmed
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pubmed-article:12552458pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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