Linked Life Data

12550111

Source:http://linkedlifedata.com/resource/pubmed/id/12550111

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2003-1-28
pubmed:abstractText
Angiogenesis (the formation of new blood vessels) is essential for the growth of new tissue, tissue repair and wound healing. Tissue engineering, the construction of new tissue and organs for reparative purposes, relies on angiogenesis for the vascularisation of these new grafts. In tissue engineering, the emphasis to date has been on vascularisation of newly constructed tissue grafts by an extrinsic blood supply, and relatively little attention has been given to the possibility of building these grafts around an intrinsic blood supply. However, there are many disease processes, notably tumour growth, where excess angiogenesis can be a major problem. The purposes of this review are, first, to examine various methods of vascularising tissue-engineered grafts, and, second, to compare the role of angiogenesis in tissue engineering, where stimulation of angiogenesis is paramount, with pathological states, such as tumour growth, where angiogenesis needs to be inhibited.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0007-1226
pubmed:author
pubmed:copyrightInfo
Copyright 2002 The British Association of Plastic Surgeons. Published by Elsevier Science Ltd. All rights reserved.
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
603-10
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Vascularisation of tissue-engineered grafts: the regulation of angiogenesis in reconstructive surgery and in disease states.
pubmed:affiliation
Bernard O'Brien Institute of Microsurgery, St Vincent's Hospital Melbourne, Fitzroy, Australia.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't