The AMP-activated protein kinase (AMPK) is a metabolic-stress-sensing protein kinase that regulates metabolism in response to energy demand and supply by directly phosphorylating rate-limiting enzymes in metabolic pathways as well as controlling gene expression.
St. Vincent's Institute of Medical Research, and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, Vic. 3065, Australia. kemp@ariel.unimelb.edu.au
