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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2003-1-24
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pubmed:abstractText |
Therapeutic cerebral angiogenesis, utilizing angiogenic factors to enhance collateral vessel formation within the central nervous system, is a potential method for cerebral revascularization. A prior dose-response study determined that intracerebroventricular infusion of vascular endothelial growth factor (VEGF) increases vascular density with minimal associated brain edema at a concentration of 5 microg/ml. The purpose of this study was to assess effects of intracerebroventricular infusion of VEGF (5 microg/ml) on cerebral blood flow, infarct volume, and brain edema after ischemia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0001-6268
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
49-53
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:12545262-Animals,
pubmed-meshheading:12545262-Brain Edema,
pubmed-meshheading:12545262-Brain Infarction,
pubmed-meshheading:12545262-Cerebrovascular Circulation,
pubmed-meshheading:12545262-Disease Models, Animal,
pubmed-meshheading:12545262-Endothelial Growth Factors,
pubmed-meshheading:12545262-Humans,
pubmed-meshheading:12545262-Infarction, Middle Cerebral Artery,
pubmed-meshheading:12545262-Infusions, Parenteral,
pubmed-meshheading:12545262-Injections, Intraventricular,
pubmed-meshheading:12545262-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:12545262-Lymphokines,
pubmed-meshheading:12545262-Neovascularization, Physiologic,
pubmed-meshheading:12545262-Rats,
pubmed-meshheading:12545262-Rats, Sprague-Dawley,
pubmed-meshheading:12545262-Severity of Illness Index,
pubmed-meshheading:12545262-Vascular Endothelial Growth Factor A,
pubmed-meshheading:12545262-Vascular Endothelial Growth Factors
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pubmed:year |
2003
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pubmed:articleTitle |
Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume.
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pubmed:affiliation |
Department of Neurosurgery, University of Michigan Health System, Ann Arbor 48109, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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