Source:http://linkedlifedata.com/resource/pubmed/id/12539154
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2003-1-22
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pubmed:abstractText |
Gene therapy is very promising in the treatment of rheumatoid arthritis (RA). Electrotransfer is a recent method reported to enhance in vivo intramuscular DNA transfection. Interleukin-10 (IL-10) has antiinflammatory effects in RA and in collagen-induced arthritis (CIA), a murine model of RA. In order to improve our strategy of gene therapy, we used electrotransfer to enhance penetration into skeletal muscle with CIA of plasmids encoding IL-10.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1099-498X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2002 John Wiley & Sons, Ltd.
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pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
164-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12539154-Animals,
pubmed-meshheading:12539154-Arthritis, Experimental,
pubmed-meshheading:12539154-Electrochemistry,
pubmed-meshheading:12539154-Gene Therapy,
pubmed-meshheading:12539154-Gene Transfer Techniques,
pubmed-meshheading:12539154-Humans,
pubmed-meshheading:12539154-Interleukin-10,
pubmed-meshheading:12539154-Knee Joint,
pubmed-meshheading:12539154-Male,
pubmed-meshheading:12539154-Mice,
pubmed-meshheading:12539154-Mice, Inbred DBA,
pubmed-meshheading:12539154-Muscle, Skeletal,
pubmed-meshheading:12539154-Plasmids
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pubmed:year |
2003
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pubmed:articleTitle |
Efficacy of interleukin-10 gene electrotransfer into skeletal muscle in mice with collagen-induced arthritis.
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pubmed:affiliation |
UPRES EA-3408 and Department of Rheumatology, Claude Bernard Foundation, Medical School of Bobigny, University of Paris 13, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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