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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1976-5-20
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pubmed:abstractText |
Phenazone metabolism was studied in 14 patients with liver disease and six normal volunteers. The plasma and renal clearance of phenazone and the 4-hydrozyphenazone excretion in urine was significantly decreased in the patients with liver disease. The urinary excretion of 4-hydroxyphenazone was significantly correlated to the plasma clearance of phenazone (r= + 0.95, P less than 0.001), to quantitative liver function as measured by the galactose elimination capacity (r= + 0.95, P less than 0.001), and to the prothrombin values (r= + 0.82, P less than 0.001). The determination of the 4-hydroxyphenazone excretion in urine may be used as an easy and non-invasive test of quantitative liver function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0014-2972
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1253807-Adult,
pubmed-meshheading:1253807-Aged,
pubmed-meshheading:1253807-Antipyrine,
pubmed-meshheading:1253807-Creatinine,
pubmed-meshheading:1253807-Galactose,
pubmed-meshheading:1253807-Humans,
pubmed-meshheading:1253807-Injections, Intravenous,
pubmed-meshheading:1253807-Kinetics,
pubmed-meshheading:1253807-Liver Diseases,
pubmed-meshheading:1253807-Liver Function Tests,
pubmed-meshheading:1253807-Male,
pubmed-meshheading:1253807-Middle Aged
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pubmed:year |
1976
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pubmed:articleTitle |
Phenazone metabolism in patients with liver disease.
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pubmed:publicationType |
Journal Article
|