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rdf:type |
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lifeskim:mentions |
umls-concept:C0002630,
umls-concept:C0007634,
umls-concept:C0017262,
umls-concept:C0035696,
umls-concept:C0079411,
umls-concept:C0185117,
umls-concept:C1280500,
umls-concept:C1522449,
umls-concept:C1555707,
umls-concept:C1705851,
umls-concept:C2752151,
umls-concept:C2828366,
umls-concept:C2911684
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pubmed:issue |
6
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pubmed:dateCreated |
2003-1-21
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pubmed:abstractText |
Amniotic membrane (AM) is the innermost fetal membrane, which contains several proteinase inhibitors and expresses several growth factors. Nitric oxide (NO) has been implicated in the pathogenesis of various inflammatory diseases including sunburn and ultraviolet induced erythema. The expression of inducible nitric oxide synthase (iNOS) is up regulated by UVB irradiation and inhibited by TGF-beta and EGF-beta. We evaluated the effect of AM extract on the expression of iNOS mRNA by UV irradiation in HaCaT cell (immortalized human keratinocyte cell line).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0905-4383
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
280-6
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pubmed:dateRevised |
2011-10-27
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pubmed:meshHeading |
pubmed-meshheading:12535023-Amnion,
pubmed-meshheading:12535023-Cell Survival,
pubmed-meshheading:12535023-Cells, Cultured,
pubmed-meshheading:12535023-DNA Primers,
pubmed-meshheading:12535023-Gene Expression Regulation,
pubmed-meshheading:12535023-Humans,
pubmed-meshheading:12535023-Keratinocytes,
pubmed-meshheading:12535023-Nitric Oxide,
pubmed-meshheading:12535023-Nitric Oxide Synthase,
pubmed-meshheading:12535023-Nitric Oxide Synthase Type II,
pubmed-meshheading:12535023-RNA, Messenger,
pubmed-meshheading:12535023-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12535023-Ultraviolet Rays
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pubmed:year |
2002
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pubmed:articleTitle |
The effect of amniotic membrane extract on the expression of iNOS mRNA and generation of NO in HaCaT cell by ultraviolet B irradiation.
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pubmed:affiliation |
Department of Dermatology, Yongsan Hospital, Chung Ang University School of Medicine, Seoul, Korea.
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pubmed:publicationType |
Journal Article
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