Linked Life Data

12533748

Source:http://linkedlifedata.com/resource/pubmed/id/12533748

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-1-20
pubmed:abstractText
We demonstrated selective activation of caspases in the thymus during heat shock, i.e. primary activation of initiator caspase 9 (but not caspase 8) and effector caspase 3 (but not caspase 6). Preadaptation to heat improved animal survival after heat shock and reduced heat shock-induced activation of both initiator and effector caspases. Hence, adaptation to heat produced an antiapoptotic effect, which was not selective towards receptor-dependent or mitochondrial pathway of the caspase cascade activation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0007-4888
pubmed:author
pubmed:issnType
Print
pubmed:volume
134
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
321-4
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Adaptation to heat limits stress-induced activation of caspases in the thymus.
pubmed:affiliation
Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't