Linked Life Data

12531402

Source:http://linkedlifedata.com/resource/pubmed/id/12531402

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2003-1-17
pubmed:abstractText
The present experiment was carried out to examine the possible effects of whole body heating on the baroreflex control of muscle sympathetic nerve activity (MSNA) and heart rate (HR). Nine healthy male volunteers underwent the Valsalva maneuver during exposure to heat stress using a hot water-perfused suit. To exclude an effect from the unloading of the cardiopulmonary baroreceptors during hyperthermia, the central hypovolemia was counterbalanced by head-down tilt (HDT) at 8 degrees. The baroreflex slopes of MSNA and HR against mean arterial pressure were determined by regression analysis during the early phase II (falling blood pressure period) of the Valsalva maneuver. The core temperature increased from 36.9 +/- 0.1 degrees C at thermoneutral to 37.7 +/- 0.1 degrees C during heat exposure, whereas the left atrial diameter (LAD) decreased. Both the MSNA and HR increased (P < 0.05) during hyperthermia. The baroreflex slopes of MSNA and HR in the phase II decreased 30 +/- 8% (P < 0.05) and 24 +/- 9% (P < 0.05), respectively, during hyperthermia. The HDT increased LAD, but there was no change in HR, arterial pressure and the baroreflex slopes. These results suggest that hyperthermia reduces the baroreflex responses of MSNA and HR during a transient falling period of blood pressure. These reduced baroreflex responses may not be attributable to an unloading of the cardiopulmonary baroreceptors during heat stress.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1566-0702
pubmed:author
pubmed:copyrightInfo
Copyright 2002 Elsevier Science B.V.
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
103
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
93-9
pubmed:dateRevised
2009-8-12
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Whole body heating reduces the baroreflex response of sympathetic nerve activity during Valsalva straining.
pubmed:affiliation
Department of Clinical Pathophysiology, School of Health Sciences, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, 807-8555 Kitakyushu, Japan. yamazaki@health.uoeh-u.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't