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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2003-1-15
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pubmed:abstractText |
Abnormalities of energy metabolism are often cited as key elements in the progressive worsening of left ventricular (LV) dysfunction that characterizes the heart failure (HF) state. The present study tested the hypothesis that partial inhibition of fatty acids will ameliorate the hemodynamic abnormalities associated with HF.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1071-9164
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
416-22
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12528095-3-Hydroxyacyl CoA Dehydrogenases,
pubmed-meshheading:12528095-Acetanilides,
pubmed-meshheading:12528095-Acetyl-CoA C-Acyltransferase,
pubmed-meshheading:12528095-Animals,
pubmed-meshheading:12528095-Carbon-Carbon Double Bond Isomerases,
pubmed-meshheading:12528095-Chronic Disease,
pubmed-meshheading:12528095-Disease Models, Animal,
pubmed-meshheading:12528095-Dogs,
pubmed-meshheading:12528095-Enoyl-CoA Hydratase,
pubmed-meshheading:12528095-Enzyme Inhibitors,
pubmed-meshheading:12528095-Heart Failure,
pubmed-meshheading:12528095-Heart Ventricles,
pubmed-meshheading:12528095-Hemodynamics,
pubmed-meshheading:12528095-Injections, Intravenous,
pubmed-meshheading:12528095-Models, Cardiovascular,
pubmed-meshheading:12528095-Piperazines,
pubmed-meshheading:12528095-Racemases and Epimerases,
pubmed-meshheading:12528095-Stroke Volume,
pubmed-meshheading:12528095-Ventricular Dysfunction, Left,
pubmed-meshheading:12528095-Ventricular Function, Left
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pubmed:year |
2002
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pubmed:articleTitle |
Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure.
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pubmed:affiliation |
Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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