Linked Life Data

12525015

Source:http://linkedlifedata.com/resource/pubmed/id/12525015

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-1-14
pubmed:abstractText
Literature data on the pathogenesis of mixed infection caused by human immunodeficiency viruses (HIV), type I, and hepatitis C virus (HCV), as well as on possible mechanisms of the reciprocal influence of these viruses necessary to understand their co-existence, are reviewed. The extrahepatic replication of HCV, its role in the infectious process and its possible contribution to the course of mono- and co-infection are considered in detail. Much attention is paid to the specific features of immune response in HIV-HCV infection and the immunomediated mechanisms of the reciprocal influence of the viruses. The problem of the hepatotoxicity of antiretrovirus preparations, actively discussed in literature, is considered from biological positions. The role of the phenomenon of immunity reconstitution in cases of the exacerbation of chronic HCV infection in the course of the treatment of HIV infection as well as of other factors, in particular, infections caused by other parenterally transmitted viruses, in the course of HIV-HCV co-infection is pointed out.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0372-9311
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
104-15
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:articleTitle
[Possible mechanisms of the reciprocal influence of infections caused by HIV and hepatitis C virus].
pubmed:affiliation
Federal Research and Methodological Center for Prophylaxis and Control of AIDS, Moscow, Russia.
pubmed:publicationType
Journal Article, English Abstract, Review