pubmed-article:12524142 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12524142 | lifeskim:mentions | umls-concept:C0009170 | lld:lifeskim |
pubmed-article:12524142 | lifeskim:mentions | umls-concept:C0025936 | lld:lifeskim |
pubmed-article:12524142 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
pubmed-article:12524142 | lifeskim:mentions | umls-concept:C0295352 | lld:lifeskim |
pubmed-article:12524142 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
pubmed-article:12524142 | lifeskim:mentions | umls-concept:C0920644 | lld:lifeskim |
pubmed-article:12524142 | pubmed:issue | 2-3 | lld:pubmed |
pubmed-article:12524142 | pubmed:dateCreated | 2003-1-13 | lld:pubmed |
pubmed-article:12524142 | pubmed:abstractText | Studies have shown that cocaine alters the function of recombinant 5-HT(3) receptors and that behavioral responses to cocaine are affected by 5-HT(3) receptor ligands. However, the actions of cocaine on brain 5-HT(3) receptors have not been characterized because these receptors are not abundantly expressed in most neuronal populations. We examined the effect of cocaine on 5-HT(3) receptor function in cultured hippocampal neurons from transgenic mice overexpressing the receptor. Cocaine competitively inhibited 5-HT(3) receptors with an IC(50) of approximately 4 microM, indicating that brain 5-HT(3) receptors are important targets for the actions of this commonly abused substance. | lld:pubmed |
pubmed-article:12524142 | pubmed:language | eng | lld:pubmed |
pubmed-article:12524142 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12524142 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:12524142 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12524142 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12524142 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12524142 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12524142 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12524142 | pubmed:month | Jan | lld:pubmed |
pubmed-article:12524142 | pubmed:issn | 0014-2999 | lld:pubmed |
pubmed-article:12524142 | pubmed:author | pubmed-author:CartaMarioM | lld:pubmed |
pubmed-article:12524142 | pubmed:author | pubmed-author:ValenzuelaC... | lld:pubmed |
pubmed-article:12524142 | pubmed:author | pubmed-author:PartridgeL... | lld:pubmed |
pubmed-article:12524142 | pubmed:author | pubmed-author:AllanAndrea... | lld:pubmed |
pubmed-article:12524142 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12524142 | pubmed:day | 17 | lld:pubmed |
pubmed-article:12524142 | pubmed:volume | 459 | lld:pubmed |
pubmed-article:12524142 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12524142 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12524142 | pubmed:pagination | 167-9 | lld:pubmed |
pubmed-article:12524142 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:12524142 | pubmed:meshHeading | pubmed-meshheading:12524142... | lld:pubmed |
pubmed-article:12524142 | pubmed:meshHeading | pubmed-meshheading:12524142... | lld:pubmed |
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pubmed-article:12524142 | pubmed:meshHeading | pubmed-meshheading:12524142... | lld:pubmed |
pubmed-article:12524142 | pubmed:meshHeading | pubmed-meshheading:12524142... | lld:pubmed |
pubmed-article:12524142 | pubmed:meshHeading | pubmed-meshheading:12524142... | lld:pubmed |
pubmed-article:12524142 | pubmed:meshHeading | pubmed-meshheading:12524142... | lld:pubmed |
pubmed-article:12524142 | pubmed:meshHeading | pubmed-meshheading:12524142... | lld:pubmed |
pubmed-article:12524142 | pubmed:meshHeading | pubmed-meshheading:12524142... | lld:pubmed |
pubmed-article:12524142 | pubmed:meshHeading | pubmed-meshheading:12524142... | lld:pubmed |
pubmed-article:12524142 | pubmed:year | 2003 | lld:pubmed |
pubmed-article:12524142 | pubmed:articleTitle | Cocaine inhibits 5-HT3 receptor function in neurons from transgenic mice overexpressing the receptor. | lld:pubmed |
pubmed-article:12524142 | pubmed:affiliation | Department of Neurosciences, University of New Mexico Health Sciences Center, Basic Medical Sciences Building, Room 145, Albuquerque, NM 87131-5223, USA. | lld:pubmed |
pubmed-article:12524142 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:12524142 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:12524142 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |