Linked Life Data

12522570

Source:http://linkedlifedata.com/resource/pubmed/id/12522570

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2003-1-10
pubmed:abstractText
Current findings suggest that multipotent stem cells may be suitable for cell replacement therapies in the treatment of neurodegenerative disorders. Embryonic stem (ES) cells are pluripotent cells isolated from the inner cell mass of the preimplantation blastocyst, which give rise to all cells in the organism. Similarly, multipotent stem cells are also able to regenerate, but are believed to have a more restricted potential than ES cells, and are often defined by the organ from which they are derived. Neural stem cells have been categorized as multipotent stem cells derived from the nervous system with the capacity to regenerate and to give rise to cells belonging to all three cell lineages in the nervous system: neurons, oligodendrocytes, and astrocytes. It is hoped that research on stem cells may reveal methods for producing an infinite supply of dopamine neurons for transplant into Parkinson's disease (PD) patients. The problem is controlling cell growth and differentiation. We will briefly review the current state of stem cell research and will critically discuss the potential of stem cells for the treatment of PD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0340-5354
pubmed:author
pubmed:issnType
Print
pubmed:volume
249 Suppl 3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
III/33-5
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Current state of stem cell research for the treatment of Parkinson's disease.
pubmed:affiliation
Klinische Neurochemie, Universitätsklinik für Kinder- und Jugendpsychiatrie und Psychotherapie, Füchsleinstrasse 15, 97080 Würzburg, Germany. manfred.gerlach@mail.uni-wuerzburg.de
pubmed:publicationType
Journal Article, Review