rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
12
|
pubmed:dateCreated |
2003-1-9
|
pubmed:abstractText |
Hirschsprung disease is characterized by segmental aganglionosis of the terminal bowel. Neurons of the enteric nervous system arise from neural crest, migrate and colonize intestinal muscle coat where they proliferate and differentiate. The first pathophysiologic hypothesis suggests an absence of neural cell migration. The most recent hypothesis involves disorders of their homing and/or their differentiation due to an altered intestinal microenvironment.
|
pubmed:language |
fre
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0399-8320
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
26
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1110-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12520199-Adult,
pubmed-meshheading:12520199-Child, Preschool,
pubmed-meshheading:12520199-DNA-Binding Proteins,
pubmed-meshheading:12520199-Gene Amplification,
pubmed-meshheading:12520199-Gene Expression Regulation,
pubmed-meshheading:12520199-Hirschsprung Disease,
pubmed-meshheading:12520199-Homeodomain Proteins,
pubmed-meshheading:12520199-Humans,
pubmed-meshheading:12520199-Muscle, Smooth,
pubmed-meshheading:12520199-Neoplasm Proteins,
pubmed-meshheading:12520199-Phenotype,
pubmed-meshheading:12520199-Reverse Transcriptase Polymerase Chain Reaction
|
pubmed:year |
2002
|
pubmed:articleTitle |
[Increased expression of HOXA9 gene in Hirschsprung disease].
|
pubmed:affiliation |
INSERM Unité 381, Ontogenèse et Pathologie du Système Digestif, 3, avenue Molière, 67200 Strasbourg, France.
|
pubmed:publicationType |
Journal Article,
English Abstract
|