Source:http://linkedlifedata.com/resource/pubmed/id/12520143
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-1-9
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pubmed:abstractText |
To identify high-risk patients with Brugada syndrome, the present study reviewed 60 standard 12-lead electrocardiograms from 60 patients collected by the Japanese Brugada syndrome registry. Under blinded conditions, the S wave of lead V(1) was measured from the tip of r to r', and the amplitude of the ST segment in lead V(2) was measured at 0.08 s from the J point. In patients with ventricular fibrillation (n=17), the S wave was significantly longer in V(1) (0.085+/-0.007 s vs 0.075+/-0.011 s, p=0.001), and ST segment elevation in V(2) was significantly greater (0.323+/-0.133 mV vs 0.236+/-0.129 mV, p=0.012) than in patients without fibrillation. An S wave width of 0.08 s or more in V(1) had a positive predictive value of 40.5% and negative predictive value of 100% for ventricular fibrillation, with 100% sensitivity. ST elevation of 0.18 mV or more in V(2) had a positive predictive value of 37.8% and a negative predictive value of 100% for ventricular fibrillation, with 100% sensitivity. Both an S wave width > or =0.08 s in V(1) and ST elevation > or =0.18 mV in V(2) were highly specific indicators of ventricular fibrillation and are proposed as new criteria for high-risk Brugada syndrome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1346-9843
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
8-10
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12520143-Adult,
pubmed-meshheading:12520143-Bundle-Branch Block,
pubmed-meshheading:12520143-Electrocardiography,
pubmed-meshheading:12520143-Female,
pubmed-meshheading:12520143-Humans,
pubmed-meshheading:12520143-Male,
pubmed-meshheading:12520143-Middle Aged,
pubmed-meshheading:12520143-Predictive Value of Tests,
pubmed-meshheading:12520143-Registries,
pubmed-meshheading:12520143-Retrospective Studies,
pubmed-meshheading:12520143-Risk Factors,
pubmed-meshheading:12520143-Sensitivity and Specificity,
pubmed-meshheading:12520143-Single-Blind Method
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pubmed:year |
2003
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pubmed:articleTitle |
New ECG criteria for high-risk Brugada syndrome.
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pubmed:affiliation |
Department of Internal Medicine, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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