Source:http://linkedlifedata.com/resource/pubmed/id/12520142
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-1-9
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pubmed:abstractText |
A review of admission records identified 194 episodes of infective endocarditis (IE) from January 1980 to December 1999 at a community hospital in Tokyo. The cases were divided into decades, and the clinical picture and short-term outcomes were compared and analyzed. The mean age of patients in the 1990s was older (45.5 +/-13.2 vs 55.1+/-12.6 years, p<0.001), and prosthetic valve endocarditis was significantly more frequently seen (14.4% vs 31.8%, p=0.004). None had a history of intravenous drug abuse (IVDA). Patients on chronic hemodialysis comprised 5.8% of IE cases in the 90s. Overall, dental procedure or caries still remained the main presumed source of infection. Staphylococcal IE showed a tendency to increase, and methicillin-resistant staphylococcal IE was significantly prominent in the 90s (0% vs 10.4%, p=0.0006). The overall in-hospital mortality was similar between the 2 groups (13.6% vs 18.8%, NS). Multivariate analysis found neurological abnormality, renal insufficiency and staphylococcal IE as predictors of in-hospital mortality. The characteristics of IE in Japan have changed, even among non-IVDA patients, and it appears to occur in a more high-risk patient population, which may warrant a more aggressive therapeutic approach to its management and treatment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1346-9843
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12520142-Adolescent,
pubmed-meshheading:12520142-Adult,
pubmed-meshheading:12520142-Aged,
pubmed-meshheading:12520142-Aged, 80 and over,
pubmed-meshheading:12520142-Child,
pubmed-meshheading:12520142-Echocardiography,
pubmed-meshheading:12520142-Endocarditis, Bacterial,
pubmed-meshheading:12520142-Female,
pubmed-meshheading:12520142-Humans,
pubmed-meshheading:12520142-Male,
pubmed-meshheading:12520142-Middle Aged,
pubmed-meshheading:12520142-Retrospective Studies,
pubmed-meshheading:12520142-Risk Factors,
pubmed-meshheading:12520142-Staphylococcal Infections
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pubmed:year |
2003
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pubmed:articleTitle |
Changing spectrum of infective endocarditis: review of 194 episodes over 20 years.
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pubmed:affiliation |
Department of Geriatric Medicine, University of Tokyo, Japan.
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pubmed:publicationType |
Journal Article
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