Linked Life Data

1251745

Source:http://linkedlifedata.com/resource/pubmed/id/1251745

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1976-4-15
pubmed:abstractText
Gastrin concentrations were measured in the gastric blood of eviscerated cats. Blood flow was recorded concomitantly thus enabling quantitative determination of the gastrin output. Electrical vagal stimulation within the "physiological" frequency range (0.5-3 Hz) did not regularly result in any detectable changes in the peripheral gastrin level but an increase in this level was always observed on stimulation with frequencies above 3 Hz. A constant gastrin release per stimulus was then obtained, as long as the total number of vagal stimuli did not exceed 2,000-3,000. A larger number of impulses resulted in rapid fatigue of the release mechanism, indicating either a rapid and sustained fatigue of the neural control mechanism or the existence of a rather small pool of gastrin for immediate release-amounting to less than one per cent of the total antral store of immunoreactive gastrin. The rate at which such a releasable pool was refilled would suffice to compensate for the depletion induced by vagal stimuli at physiological frequencies i.e. less then 3-4 Hz only. The two vagi innervate separate gastrin pools, which behave independently as far as release and refilling are concerned.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0001-6772
pubmed:author
pubmed:issnType
Print
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-28
pubmed:dateRevised
2009-10-27
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Quantitative aspects of the vagal control of gastrin release in cats.
pubmed:publicationType
Journal Article