pubmed-article:12512026 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12512026 | lifeskim:mentions | umls-concept:C0012655 | lld:lifeskim |
pubmed-article:12512026 | lifeskim:mentions | umls-concept:C0009324 | lld:lifeskim |
pubmed-article:12512026 | lifeskim:mentions | umls-concept:C1704939 | lld:lifeskim |
pubmed-article:12512026 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
pubmed-article:12512026 | lifeskim:mentions | umls-concept:C0678951 | lld:lifeskim |
pubmed-article:12512026 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:12512026 | pubmed:dateCreated | 2003-1-3 | lld:pubmed |
pubmed-article:12512026 | pubmed:abstractText | The human multidrug resistance 1 (MDR1) gene product P-glycoprotein is highly expressed in intestinal epithelial cells, where it constitutes a barrier against xenobiotics. The finding that mdr1a knockout mice develop a form of colitis that is similar to ulcerative colitis, which can be prevented by antibiotics, indicates a barrier function for P-glycoprotein against the invasion of bacteria or toxins. Because the MDR1 single nucleotide polymorphism C3435T is associated with lower intestinal P-glycoprotein expression, we tested whether this polymorphism predisposes to development of ulcerative colitis. | lld:pubmed |
pubmed-article:12512026 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12512026 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12512026 | pubmed:language | eng | lld:pubmed |
pubmed-article:12512026 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12512026 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:12512026 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12512026 | pubmed:month | Jan | lld:pubmed |
pubmed-article:12512026 | pubmed:issn | 0016-5085 | lld:pubmed |
pubmed-article:12512026 | pubmed:author | pubmed-author:EichelbaumMic... | lld:pubmed |
pubmed-article:12512026 | pubmed:author | pubmed-author:SchwabMatthia... | lld:pubmed |
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pubmed-article:12512026 | pubmed:author | pubmed-author:GregorMichael... | lld:pubmed |
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pubmed-article:12512026 | pubmed:author | pubmed-author:MetzlerJoergJ | lld:pubmed |
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pubmed-article:12512026 | pubmed:author | pubmed-author:KaskasBerndB | lld:pubmed |
pubmed-article:12512026 | pubmed:author | pubmed-author:StangeEduardE | lld:pubmed |
pubmed-article:12512026 | pubmed:author | pubmed-author:SchoelmerichJ... | lld:pubmed |
pubmed-article:12512026 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12512026 | pubmed:volume | 124 | lld:pubmed |
pubmed-article:12512026 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12512026 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12512026 | pubmed:pagination | 26-33 | lld:pubmed |
pubmed-article:12512026 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:12512026 | pubmed:year | 2003 | lld:pubmed |
pubmed-article:12512026 | pubmed:articleTitle | Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis. | lld:pubmed |
pubmed-article:12512026 | pubmed:affiliation | Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Auerbachstrasse 112, 70376 Stuttgart, Germany. matthias.schwab@kp-stuttgart.de | lld:pubmed |
pubmed-article:12512026 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:12512026 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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