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rdf:type |
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lifeskim:mentions |
umls-concept:C0001811,
umls-concept:C0026809,
umls-concept:C0180683,
umls-concept:C0206427,
umls-concept:C0599295,
umls-concept:C1527148,
umls-concept:C1551083,
umls-concept:C1552915,
umls-concept:C1705186,
umls-concept:C1707520,
umls-concept:C1710082,
umls-concept:C1947942,
umls-concept:C2347970,
umls-concept:C2347971,
umls-concept:C2355587
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pubmed:issue |
1
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pubmed:dateCreated |
2002-12-30
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pubmed:abstractText |
RPE65 has been shown to be essential for the production of 11-cis retinal by the retinal pigment epithelium. Mutations in RPE65 are known to be associated with severe forms of early-onset retinal dystrophy. This project was designed to determine the amount of regenerable opsin in Rpe65-/- mice during development and aging, and to examine the function of this rhodopsin by electroretinography (ERG).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
310-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12506090-Aging,
pubmed-meshheading:12506090-Animals,
pubmed-meshheading:12506090-Carrier Proteins,
pubmed-meshheading:12506090-Dark Adaptation,
pubmed-meshheading:12506090-Electroretinography,
pubmed-meshheading:12506090-Eye Proteins,
pubmed-meshheading:12506090-Injections,
pubmed-meshheading:12506090-Mass Spectrometry,
pubmed-meshheading:12506090-Mice,
pubmed-meshheading:12506090-Mice, Inbred C57BL,
pubmed-meshheading:12506090-Mice, Knockout,
pubmed-meshheading:12506090-Microspectrophotometry,
pubmed-meshheading:12506090-Proteins,
pubmed-meshheading:12506090-Regeneration,
pubmed-meshheading:12506090-Retinal Rod Photoreceptor Cells,
pubmed-meshheading:12506090-Retinaldehyde,
pubmed-meshheading:12506090-Rod Opsins,
pubmed-meshheading:12506090-Vision, Ocular
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pubmed:year |
2003
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pubmed:articleTitle |
Correlation of regenerable opsin with rod ERG signal in Rpe65-/- mice during development and aging.
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pubmed:affiliation |
Department of Ophthalmology Medical University of South Carolina, 167 Ashley Avenue, Charleston, SC 29425, USA. rohrer@musc.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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