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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2002-12-30
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pubmed:abstractText |
Perineuclear anti-neutrophil cytoplasmic antibody (pANCA), a marker antibody present in 12% of patients with anterior uveitis, recognizes cytoplasmic antigens in the nonpigmented ciliary body epithelium, a probable site of immunologic reactivity in this inflammatory disease. In this study, a recombinantly isolated pANCA monoclonal antibody was used to identify the corresponding antigenic target(s) in the ciliary body.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
203-9
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pubmed:dateRevised |
2011-3-22
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pubmed:meshHeading |
pubmed-meshheading:12506076-Amino Acid Sequence,
pubmed-meshheading:12506076-Animals,
pubmed-meshheading:12506076-Antibodies, Antineutrophil Cytoplasmic,
pubmed-meshheading:12506076-Antibodies, Monoclonal,
pubmed-meshheading:12506076-Autoantibodies,
pubmed-meshheading:12506076-Autoantigens,
pubmed-meshheading:12506076-Blotting, Western,
pubmed-meshheading:12506076-Cattle,
pubmed-meshheading:12506076-Ciliary Body,
pubmed-meshheading:12506076-Humans,
pubmed-meshheading:12506076-Microscopy, Confocal,
pubmed-meshheading:12506076-Molecular Sequence Data,
pubmed-meshheading:12506076-RNA, Messenger,
pubmed-meshheading:12506076-Rabbits,
pubmed-meshheading:12506076-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12506076-Sequence Homology, Amino Acid,
pubmed-meshheading:12506076-Uveitis, Anterior,
pubmed-meshheading:12506076-beta-Crystallin B Chain
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pubmed:year |
2003
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pubmed:articleTitle |
BetaB1-crystallin: identification of a candidate ciliary body uveitis antigen.
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pubmed:affiliation |
Department of Ophthalmology, University of California-Los Angeles, Jules Stein Eye Institute, 100 Stein Plaza, Los Angeles, CA 90095, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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