Linked Life Data

12505767

Source:http://linkedlifedata.com/resource/pubmed/id/12505767

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-12-30
pubmed:abstractText
The present study addresses the difference in activities of frontal and temporal mismatch negativity (MMN) generators between healthy controls and schizophrenic patients. Auditory MMNs were measured from 13 medicated schizophrenic patients in a post-acute phase and 12 healthy controls. The probabilities of the standard stimuli were, in different experimental blocks, 95, 90, 80 or 70%. The mean amplitude of the MMN recorded at Fz was significantly smaller in schizophrenic patients than healthy controls only in the conditions with high probability of standard stimuli, while that recorded at mastoid sites was not different in any condition. The present study suggested that schizophrenic patients might fail to cause involuntary attention switch to stimulus change reflected in the lowered MMN amplitude recorded at Fz; whereas the patients might index an adequate detection of the deviant event reflected by the similar amplitude of MMN recorded at mastoid sites.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0301-0511
pubmed:author
pubmed:issnType
Print
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-63
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Impairment in activation of a frontal attention-switch mechanism in schizophrenic patients.
pubmed:affiliation
Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki 036-8562, Japan. y-sato-m@oodate.or.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't