Linked Life Data

12502320

Source:http://linkedlifedata.com/resource/pubmed/id/12502320

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2002-12-27
pubmed:abstractText
Using bioactivity-directed isolation procedures, five new spirostan saponins and two sterol glycosides have been isolated from Solanum chrysotrichum leaves. The structure of these compounds was established based upon spectroscopic measurements, especially 1D and 2D NMR data of their peracetate derivatives. These compounds showed antimycotic activity. The most active compound is 6alpha-O-beta-d-xylopyranosyl-(1-->3)-beta-d-quinovopyranosyl-(25R)-5alpha-spirostan-3beta,23alpha-ol (2) (MIC =12.5, 12.5, 100, and 200 microg/mL against Trichophyton mentagrophytes, T. rubrum, Aspergillis niger, and Candida albicans, respectively).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0163-3864
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1815-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Five new steroidal saponins from Solanum chrysotrichum leaves and their antimycotic activity.
pubmed:affiliation
Centro de Investigación Biomédica del Sur, Instituto Mexicano del Seguro Social, Argentina No. 1, Centro, 62790 Xochitepec, Morelos, México. azamilpa_2000@yahoo.com.mx
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't