Source:http://linkedlifedata.com/resource/pubmed/id/12499634
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2002-12-24
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pubmed:abstractText |
SodD, a Cu/Zn superoxide dismutase in Dictyostelium discoideum, shows 48% identity to the cytosolic Cu/Zn superoxide dismutase (SOD) of Saccharomyces cerevisiae (SOD1). The sodD gene is expressed in D. discoideum cells at late-developmental stages. However, gene expression was not detected in the sporeless mutant, indicating that sodD is a spore cell-specific gene. The D. discoideum mutant, in which sodD was disrupted, grew and formed a multicellular structure normally, therefore the gene is not essential for growth and development. The mutant spores were sensitive to UV-light compared to the wild-type spores, indicating that SodD protects spores from cellular damage caused by UV-light.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0918-6158
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1528-32
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:12499634-Amino Acid Sequence,
pubmed-meshheading:12499634-Animals,
pubmed-meshheading:12499634-Base Sequence,
pubmed-meshheading:12499634-Dictyostelium,
pubmed-meshheading:12499634-Genes,
pubmed-meshheading:12499634-Molecular Sequence Data,
pubmed-meshheading:12499634-Mutation,
pubmed-meshheading:12499634-Protozoan Proteins,
pubmed-meshheading:12499634-Sequence Analysis, DNA,
pubmed-meshheading:12499634-Sequence Homology, Amino Acid,
pubmed-meshheading:12499634-Superoxide Dismutase,
pubmed-meshheading:12499634-Ultraviolet Rays
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pubmed:year |
2002
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pubmed:articleTitle |
Analysis of the gene encoding copper/zinc superoxide dismutase homolog in Dictyostelium discoideum.
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pubmed:affiliation |
Division of Bioengineering, Faculty of Engineering, Toyama University, Japan.
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pubmed:publicationType |
Journal Article
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