Source:http://linkedlifedata.com/resource/pubmed/id/12495634
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2002-12-23
|
| pubmed:abstractText |
The medial temporal lobe (MTL) has been associated with declarative learning of flexible relational rules and the basal ganglia with implicit learning of stimulus-response mappings. It remains an open question of whether MTL or basal ganglia are involved when learning flexible relational contingencies without awareness. We studied learning of an explicit stimulus-response association with fMRI. Embedded in this explicit task was a hidden structure that was learnt implicitly. Implicit learning of the sequential regularities of the "hidden rule" activated the ventral perirhinal cortex, within the MTL, whereas learning the fixed stimulus-response associations activated the basal ganglia, indicating that the function of the MTL and the basal ganglia depends on the learned material and not necessarily on the participants' awareness.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Dec
|
| pubmed:issn |
0896-6273
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
19
|
| pubmed:volume |
36
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1221-31
|
| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:12495634-Adult,
pubmed-meshheading:12495634-Awareness,
pubmed-meshheading:12495634-Basal Ganglia,
pubmed-meshheading:12495634-Behavior,
pubmed-meshheading:12495634-Brain Mapping,
pubmed-meshheading:12495634-Cerebrovascular Circulation,
pubmed-meshheading:12495634-Conditioning, Classical,
pubmed-meshheading:12495634-Evoked Potentials,
pubmed-meshheading:12495634-Female,
pubmed-meshheading:12495634-Functional Laterality,
pubmed-meshheading:12495634-Humans,
pubmed-meshheading:12495634-Learning,
pubmed-meshheading:12495634-Magnetic Resonance Imaging,
pubmed-meshheading:12495634-Male,
pubmed-meshheading:12495634-Neuropsychological Tests,
pubmed-meshheading:12495634-Photic Stimulation,
pubmed-meshheading:12495634-Psychomotor Performance,
pubmed-meshheading:12495634-Reaction Time,
pubmed-meshheading:12495634-Temporal Lobe
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
The role of medial temporal lobe structures in implicit learning: an event-related FMRI study.
|
| pubmed:affiliation |
Cognitive Neuroscience Laboratory, Department of Neurology, University of Hamburg Medical School, D-20246, Hamburg, Germany. rose@uke.uni-hamburg.de
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|