rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2002-12-23
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pubmed:abstractText |
Recent studies suggest a complex association between smoking and retinopathy that probably depends on the interaction between many variables. We have reported an association between ACP1 phenotype and retinopathy in type 1 diabetes. Additionally, the deleterious effects of smoking on intrauterine growth are dependent on ACP1, a low-molecular-weight tyrosine phosphatase that modifies signal transduction. We examine here the interaction between smoking and ACP1 as a mediator of susceptibility to diabetic retinopathy in a sample of puerperae with type 1 diabetes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0002-9629
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
324
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
310-3
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12495297-Adult,
pubmed-meshheading:12495297-Age Factors,
pubmed-meshheading:12495297-Blood Glucose,
pubmed-meshheading:12495297-Diabetes Mellitus, Type 1,
pubmed-meshheading:12495297-Diabetic Retinopathy,
pubmed-meshheading:12495297-Epistasis, Genetic,
pubmed-meshheading:12495297-Female,
pubmed-meshheading:12495297-Glycemic Index,
pubmed-meshheading:12495297-Humans,
pubmed-meshheading:12495297-Infant, Newborn,
pubmed-meshheading:12495297-Isoenzymes,
pubmed-meshheading:12495297-Pregnancy,
pubmed-meshheading:12495297-Pregnancy in Diabetics,
pubmed-meshheading:12495297-Protein Tyrosine Phosphatase, Non-Receptor Type 1,
pubmed-meshheading:12495297-Protein Tyrosine Phosphatases,
pubmed-meshheading:12495297-Proto-Oncogene Proteins,
pubmed-meshheading:12495297-Regression Analysis,
pubmed-meshheading:12495297-Signal Transduction,
pubmed-meshheading:12495297-Smoking,
pubmed-meshheading:12495297-Statistics as Topic
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pubmed:year |
2002
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pubmed:articleTitle |
Smoking and the genetics of signal transduction: an association study on retinopathy in type 1 diabetes.
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pubmed:affiliation |
Section of Occupational Health Medicine, Department of Biopathology and Imaging Diagnostics, University of Rome Tor Vergata, Rome, Italy.
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pubmed:publicationType |
Journal Article
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