| pubmed-article:12493647 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12493647 | lifeskim:mentions | umls-concept:C0446051 | lld:lifeskim |
| pubmed-article:12493647 | lifeskim:mentions | umls-concept:C0002390 | lld:lifeskim |
| pubmed-article:12493647 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:12493647 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:12493647 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:12493647 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:12493647 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:12493647 | pubmed:dateCreated | 2003-3-28 | lld:pubmed |
| pubmed-article:12493647 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12493647 | pubmed:abstractText | The most common form of hypersensitivity pneumonitis in Japan is summer-type hypersensitivity pneumonitis (SHP), which is caused by the inhalation of Trichosporon asahii or Trichosporon mucoides. To seek protein antigens relevant to the immunopathogenesis of SHP, we constructed a cDNA expression library of T. asahii, a major causative yeast species of SHP. Using the immunoscreening method, we identified and cloned a novel gene encoding a 19-kD protein, named TA-19, which proved to be specifically recognized in the bronchoalveolar lavage (BAL) fluids and sera of patients with SHP. IgG, IgA, and IgM antibodies to the recombinant TA-19 protein were significantly elevated in the sera as well as in the BAL fluids from SHP patients compared with those from non-SHP groups. This protein also induced SHP-specific proliferation of the mononuclear cells from both the peripheral blood and BAL. These results reveal that TA-19 derived from T. asahii may play a relevant role in specific cellular and humoral immune responses in patients with SHP. | lld:pubmed |
| pubmed-article:12493647 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12493647 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12493647 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:12493647 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12493647 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12493647 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12493647 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12493647 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12493647 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12493647 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12493647 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:12493647 | pubmed:issn | 1073-449X | lld:pubmed |
| pubmed-article:12493647 | pubmed:author | pubmed-author:YoshizawaYasu... | lld:pubmed |
| pubmed-article:12493647 | pubmed:author | pubmed-author:MatsunagaYasu... | lld:pubmed |
| pubmed-article:12493647 | pubmed:author | pubmed-author:UsuiYutakaY | lld:pubmed |
| pubmed-article:12493647 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12493647 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:12493647 | pubmed:volume | 167 | lld:pubmed |
| pubmed-article:12493647 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12493647 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12493647 | pubmed:pagination | 991-8 | lld:pubmed |
| pubmed-article:12493647 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:12493647 | pubmed:meshHeading | pubmed-meshheading:12493647... | lld:pubmed |
| pubmed-article:12493647 | pubmed:meshHeading | pubmed-meshheading:12493647... | lld:pubmed |
| pubmed-article:12493647 | pubmed:meshHeading | pubmed-meshheading:12493647... | lld:pubmed |
| pubmed-article:12493647 | pubmed:meshHeading | pubmed-meshheading:12493647... | lld:pubmed |
| pubmed-article:12493647 | pubmed:meshHeading | pubmed-meshheading:12493647... | lld:pubmed |
| pubmed-article:12493647 | pubmed:meshHeading | pubmed-meshheading:12493647... | lld:pubmed |
| pubmed-article:12493647 | pubmed:meshHeading | pubmed-meshheading:12493647... | lld:pubmed |
| pubmed-article:12493647 | pubmed:meshHeading | pubmed-meshheading:12493647... | lld:pubmed |
| pubmed-article:12493647 | pubmed:meshHeading | pubmed-meshheading:12493647... | lld:pubmed |
| pubmed-article:12493647 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12493647 | pubmed:articleTitle | TA-19, a novel protein antigen of Trichosporon asahii, in summer-type hypersensitivity pneumonitis. | lld:pubmed |
| pubmed-article:12493647 | pubmed:affiliation | Department of Pulmonary Medicine, Faculty of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. | lld:pubmed |
| pubmed-article:12493647 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12493647 | pubmed:publicationType | Comparative Study | lld:pubmed |
