Linked Life Data

12493244

Source:http://linkedlifedata.com/resource/pubmed/id/12493244

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-12-20
pubmed:abstractText
Genomic imprinting, whereby certain genes are expressed dependent on whether they are maternally or paternally inherited, is restricted to mammals and angiosperm plants. This unusual mode of gene regulation results from the complex interplay between cis-regulatory elements, leading to parent-of-origin-dependent epigenetic modifications and tissue-specific patterns of imprinted gene expression. Many studies of imprinting and imprinted genes have focused on epigenetic effects, such as DNA methylation and chromatin structure. However, it is equally important to explore the interconnected role of regulatory elements at imprinted domains by genetic experiments, including the use of transgenes and deletions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0168-9525
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-23
pubmed:dateRevised
2011-10-7
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
H19 and Igf2--enhancing the confusion?
pubmed:affiliation
Wellcome Trust/Cancer Research UK Institute of Cancer and Developmental Biology, Tennis Court Road, CB2 1QR, Cambridge, UK. kat.arney@csc.mrc.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't