Source:http://linkedlifedata.com/resource/pubmed/id/12492583
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2002-12-20
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pubmed:abstractText |
t(11;18)(q21;q21), the most frequent chromosomal aberration of mucosa-associated lymphoid tissue (MALT) lymphoma, occurs in 30% of gastric patients. Although the translocation is often associated with an 'aggressive' course, it has not been described in transformed MALT lymphomas. We screened 15 gastric MALT lymphomas [three with concurrent or subsequent high-grade transformation and 11 diffuse large B-cell lymphomas (DLBCLs)] in Chinese patients for t(11;18). t(11;18) was found in 9/15 (60%) MALT lymphomas, but not in any DLBCLs. One patient, with subsequent high-grade transformation, showed the translocation in low- and high-grade lesions. t(11;18) was frequent in Chinese gastric MALT lymphomas and unusually one transformed lymphoma carried the translocation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0007-1048
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-100
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pubmed:dateRevised |
2009-11-3
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pubmed:meshHeading |
pubmed-meshheading:12492583-Adult,
pubmed-meshheading:12492583-Aged,
pubmed-meshheading:12492583-Aged, 80 and over,
pubmed-meshheading:12492583-Cell Transformation, Neoplastic,
pubmed-meshheading:12492583-Chromosomes, Human, Pair 11,
pubmed-meshheading:12492583-Chromosomes, Human, Pair 18,
pubmed-meshheading:12492583-Female,
pubmed-meshheading:12492583-Gastric Mucosa,
pubmed-meshheading:12492583-Humans,
pubmed-meshheading:12492583-Lymphoma, B-Cell, Marginal Zone,
pubmed-meshheading:12492583-Lymphoma, Large B-Cell, Diffuse,
pubmed-meshheading:12492583-Male,
pubmed-meshheading:12492583-Middle Aged,
pubmed-meshheading:12492583-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12492583-Taiwan,
pubmed-meshheading:12492583-Translocation, Genetic
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pubmed:year |
2003
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pubmed:articleTitle |
High frequency of t(11;18) in gastric mucosa-associated lymphoid tissue lymphomas in Taiwan, including one patient with high-grade transformation.
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pubmed:affiliation |
Department of Pathology, Chi-Mei Medical Centre, Tainan, Taiwan.
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pubmed:publicationType |
Journal Article
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