Linked Life Data

12487757

Source:http://linkedlifedata.com/resource/pubmed/id/12487757

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-12-18
pubmed:abstractText
The effect of Phaseolus vulgaris, an indigenous plant used in ayurvedic medicine in India, on circulatory antioxidants and lipids was studied in rats with streptozotocin-induced diabetes. Oral administration of an aqueous extract of P. vulgaris pods (PPEt, 200 mg/kg body weight) for 45 days significantly reduced the elevated blood glucose, serum triglycerides, free fatty acids, phospholipids, total cholesterol, very-low-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. The extract also caused a significant decrease in plasma thiobarbituric acid-reactive substances (TBARS), hydroperoxides, vitamin E, and ceruloplasmin. The decreased serum levels of high-density lipoprotein cholesterol, antiatherogenic index (AAI), plasma insulin, vitamin C, and glutathione in the diabetic rats were also reversed toward normalization. The results show the antioxidant and antihyperlipidemic properties of PPEt in addition to its antidiabetic action. PPEt was found to be more effective than glibenclamide.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1096-620X
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-103
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Effect of Phaseolus vulgaris on circulatory antioxidants and lipids in rats with streptozotocin-induced diabetes.
pubmed:affiliation
Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar, Tamil Nadu-608 002, India.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't