Linked Life Data

12487177

Source:http://linkedlifedata.com/resource/pubmed/id/12487177

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2002-12-18
pubmed:abstractText
A 65-year-old man was found to have a mass lesion surrounded by ground-glass attenuation in the left upper lobe on chest radiography. He was diagnosed with stage IA adenocarcinoma of the lung. The resected lung specimen revealed papillary adenocarcinoma associated with infiltralion of numerous lymphocytes in the alveolar septa, which was consistent with focal lymphocytic interstitial pneumonia (LIP). However, it was not associated with Sjögren's syndrome or any other immunologic abnormalities. Immunohistochemical study disclosed that CD8 positive T-cells constituted the major element of the infiltrated lymphocytes in the tumor, and were also found in the enlarged alveolar septa, suggesting an association between lung cancer and LIP. To our knowledge, this is the first description of an association between LIP and lung cancer. In addition, the focal LIP in this case probably reflected local immune response to an antigenic stimulus caused by lung cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0918-2918
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
997-1001
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Lung cancer with focal lymphocytic interstitial pneumonia.
pubmed:affiliation
First Department of Internal Medicine, Kagawa Medical University, Kita-gun, Kagawa.
pubmed:publicationType
Journal Article, Case Reports