Linked Life Data

1248680

Source:http://linkedlifedata.com/resource/pubmed/id/1248680

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-4-9
pubmed:abstractText
Jejunal absorption of acetate, propionate, and butyrate--the three predominant short chain fatty acids (SCFA's) in small and large intestinal contents--was studied in 5 volunteer subjects. A triple-lumen perfusion technique was employed; the test solutions were isotonic and contained 0, 5, 10, 25, 40, or 50 mM of a SCFA as the sodium salt. Intermittent secretion of small amounts of acetate and butyrate occurred during 3 of 15 control perfusion periods, and the concentrations measured in intestinal samples exceeded those reported for circulating plasma. The three SCFA's were absorbed rapidly and at equal rates. Absorption rates rose in apparently linear fashion with the mean concentration in the study segment (up to 20 mM) but reached saturation at the higher concentrations present in the mixing segment. Water and sodium absorption increased slightly during butyrate absorption. The flow rate of fasting intestinal contents did not increase during SCFA perfusion. SCFA's are readily absorbed and do not exert a diarrheogenic effect in the normal human jejunum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0016-5085
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
211-5
pubmed:dateRevised
2009-10-27
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Absorption of short chain fatty acids from the human jejunum.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.