Linked Life Data

1248647

Source:http://linkedlifedata.com/resource/pubmed/id/1248647

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-4-15
pubmed:abstractText
K-pyroantimonate is an anion that forms an electron-dense precipitate with cellular cations that is readily visualized at the ultrastructural level. The staining process is made relatively specific for calcium by comparing pyroantimonate treated sections to sections pretreated with ethylene glycol-bis-N,N'-tetraacetic acid, a chelating agent that removes calcium but not other cellular cations. By these means, it is shown that the antimonate-calcium complex is located predominantly in mitochondria and cell membranes throughout most of the growth plate. In the degenerating zone, however, there is a gradual loss of stain complex from the mitochondria and cell membranes and a concomitant accumulation of the stain complex by matrix vesicles. The latter are the initial site of mineralization in the growth plate as detected by these means. Thus, this study suggests that intracellular calcium plays a significant role in matrix calcification.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0014-9446
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
143-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Histochemical localization of calcium in growth plate mitochondria and matrix vesicles.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.