rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5 Pt 1
|
pubmed:dateCreated |
2002-12-17
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pubmed:abstractText |
Microscopic polyangeitis is a necrosing vascularitis with pulmonary and renal tropism. Localized in the lung, microscopic polyangeitis leads to intra-alveolar hemorrhage. We report our observations in two patients who presented with concomitant bronchectasia. The parallel course of these two conditions suggests a possible relationship. We propose a pathophysiological approach involving a direct role of polymorphonuclear neutrophils and neutrophilic proteases secreted in response to activation of anti-polymorphonuclear cytoplasm anti-bodies (ANCA) during microscopic polyangeitis aggravating bronchectasia.
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pubmed:language |
fre
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0761-8417
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
290-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12486380-Aged,
pubmed-meshheading:12486380-Anti-Inflammatory Agents,
pubmed-meshheading:12486380-Antibodies, Antineutrophil Cytoplasmic,
pubmed-meshheading:12486380-Biological Markers,
pubmed-meshheading:12486380-Bronchiectasis,
pubmed-meshheading:12486380-Drug Therapy, Combination,
pubmed-meshheading:12486380-Female,
pubmed-meshheading:12486380-Glomerulonephritis,
pubmed-meshheading:12486380-Humans,
pubmed-meshheading:12486380-Immunosuppressive Agents,
pubmed-meshheading:12486380-Lung,
pubmed-meshheading:12486380-Male,
pubmed-meshheading:12486380-Methylprednisolone,
pubmed-meshheading:12486380-Treatment Outcome,
pubmed-meshheading:12486380-Vasculitis
|
pubmed:year |
2002
|
pubmed:articleTitle |
[Bronchectasia and microscopic polyangeitis].
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pubmed:affiliation |
Service de Pneumologie, 2 bis, boulevard Tonnellé 37000 Tours. diot@med.uni-tours.fr
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|