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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2002-12-17
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pubmed:abstractText |
We studied the pharmacokinetics of CPT-11 with intraperitoneal administration in a patient with a PTCD tube. The patient had advanced gastric cancer with peritoneal metastasis. CPT-11 was administrated in a dose of 40 mg and the intraperitoneal, plasma and bile levels of CPT-11, SN-38 and SN-38 glucuronide (SN-38 GLU) were measured periodically. The results showed that the periodical concentration pattern of CPT-11, SN-38 and SN-38 GLU in the bile was closely related to that of CPT-11 in the abdominal cavity.
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pubmed:language |
jpn
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0385-0684
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2188-90
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pubmed:dateRevised |
2007-9-25
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pubmed:meshHeading |
pubmed-meshheading:12484033-Aged,
pubmed-meshheading:12484033-Aged, 80 and over,
pubmed-meshheading:12484033-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:12484033-Ascites,
pubmed-meshheading:12484033-Bile,
pubmed-meshheading:12484033-Camptothecin,
pubmed-meshheading:12484033-Glucuronides,
pubmed-meshheading:12484033-Humans,
pubmed-meshheading:12484033-Infusions, Parenteral,
pubmed-meshheading:12484033-Male,
pubmed-meshheading:12484033-Stomach Neoplasms
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pubmed:year |
2002
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pubmed:articleTitle |
[Pharmacokinetic study of CPT-11, SN-38 and SN-38 glucuronide in the ascites, plasma and bile after intraperitoneal administration of CPT-11].
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pubmed:affiliation |
Dept. of Surgery, Tokyo Metropolitan Ohkubo Hospital.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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