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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2002-12-16
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pubmed:abstractText |
An accelerated rate of glucose metabolism mediated by overexpression of key regulatory glycolytic enzymes and glucose transporters is among the most characteristic biochemical marker of malignant transformed cells. In thyroid neoplasms, however, an increased uptake of glucose [measured by 2-[18F]-fluoro-2-deoxy-D-glucose (FDG) and positron emission tomography (PET)] seems to be restricted to more aggressive and high-grade tumors, whereas tumors with favorable prognosis demonstrate no significant tracer uptake. We therefore studied the expression of glucose transporters in thyroid carcinomas with different grades of malignancy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Excitatory Amino Acid Transporter 2,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose Transporter Type 2,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose Transporter Type 3,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose Transporter Type 4,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose Transporter Type 5,
http://linkedlifedata.com/resource/pubmed/chemical/Ki-67 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Monosaccharide Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Muscle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/SLC2A3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/SLC2A4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1050-7256
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
747-54
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:12481939-Excitatory Amino Acid Transporter 2,
pubmed-meshheading:12481939-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:12481939-Glucose Transporter Type 2,
pubmed-meshheading:12481939-Glucose Transporter Type 3,
pubmed-meshheading:12481939-Glucose Transporter Type 4,
pubmed-meshheading:12481939-Glucose Transporter Type 5,
pubmed-meshheading:12481939-Humans,
pubmed-meshheading:12481939-Immunohistochemistry,
pubmed-meshheading:12481939-Ki-67 Antigen,
pubmed-meshheading:12481939-Monosaccharide Transport Proteins,
pubmed-meshheading:12481939-Muscle Proteins,
pubmed-meshheading:12481939-Nerve Tissue Proteins,
pubmed-meshheading:12481939-Predictive Value of Tests,
pubmed-meshheading:12481939-Prognosis,
pubmed-meshheading:12481939-Risk Factors,
pubmed-meshheading:12481939-Thyroid Neoplasms,
pubmed-meshheading:12481939-Tumor Markers, Biological
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pubmed:year |
2002
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pubmed:articleTitle |
Glucose transporter 1 gene expression is related to thyroid neoplasms with an unfavorable prognosis: an immunohistochemical study.
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pubmed:affiliation |
Department of Nuclear Medicine, University of Regensburg, Germany. johann.schoenberger@klinik.uni-regensburg.de
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pubmed:publicationType |
Journal Article
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